Dog treats. Advanced oral care. Loves since 1908. Clinically proven to help freshen breath. As effective as brushing (When fed daily, Milk-Bone Brushing Chews are as effective as brushing a dog's teeth a twice a week based on the reduction of tartar build-up and bad breath. The Veterinary Oral Health Council recommends daily tooth brushing for optimal effectiveness). Advanced oral care with fresh breath helps give your dog a healthy, happy life. Nubs & ridges designed to help clean like bristles on a toothbrush. Fights tartar build-up and bad breath. Daily Milk-Bone Brushing Chews. Yearly veterinary dental checkup. Helps clean even hard to reach back teeth and down to the gumline. Veterinary Oral Health Council. VOHC accepted. Helps control tartar. See bottom panel for details. See bottom panel for product information. For dogs 5-24 lb. Not suitable for dogs less than 5 lb, greater than 24 lb or dogs less than 6 months. Fortified with essential vitamins and minerals, including calcium to help support strong bones and teeth. Milk-Bone advanced oral care. Comments or questions? Call 1-888-MilkBone (645-5266), weekdays. Please provide product manufacturing code. www.milkbone.com. Calorie Content (calculated): Metabolizable Energy (ME) 2580 kcal/kg; 31 kcal/piece. Produced in Topeka Kansas, USA.